Notre Dame College, Dhaka, is a degree college affiliated with the National University. Shortly after the formation of Pakistan, the then Archbishop of Dhaka, His Grace Lawrence L Graner CSC, invited the Priest Society of the Congregation of Holy Cross to establish a college in Dhaka. Accordingly the priests assigned to this task obtained permission from the Religious Brothers of Holy Cross and in November 1949 started a college on the campus of St. Gregory School, Luxmibazar, giving it the name St. Gregory College. Though the initial institution was humble, the aim was lofty: to spread the light of education in the eastern part of the newly born country, Pakistan. Since its inception, the college has been administered by the priests of the Congregation of Holy Cross.
 
In 1955 the college was relocated to its present site in the Motijheel area of Dhaka and renamed “Notre Dame College”. Even though it is a Degree College, most students study in the intermediate level for two years (classes XI and XII), taking classes in Science, Business Studies or Arts. In the three-year Degree program classes are offered leading to a Bachelor Degree of Arts (B.A. Pass Course) or a Bachelor of Social Sciences (B.S.S. Pass Course). 

 Besides the regular academic courses in the Intermediate and Degree levels, an English Program (English as a Foreign Language) is conducted almost all year round and is open to all. As an expression of social concern, the College conducts Literacy classes (I to VIII) for slum children, in three shifts, morning, afternoon and evening. About 1150 students attend the Literacy School.